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    CD1B Polyclonal Antibody

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    ¥1900.00元/format:100ul

    目錄號:IPB0007

    庫存:現貨
    規格

    產品信息

    Catalog No?:IPB0007
    Reactivity:Human; Mouse; Rat
    Applications:IHC-p; ELISA
    Dilution:IHC-p: 1:100-1:200 ELISA: 1:10000-20000
    Gene Name:CD1B
    Protein Name:T-cell surface glycoprotein CD1b (CD antigen CD1b)
    Human Gene Id:910
    Swiss-Prot:P29016
    Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
    Source:Rabbit
    Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Concentration:1 mg/ml
    Storage&Stability:-20°C/1 year
    Subcellular Location:Cell membrane; Single-pass type I membrane protein Endosome membrane; Single-pass type I membrane protein Lysosome membrane; Single-pass type I membrane protein Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes
    MW:-
    Background:This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells The human genome contains five CD1 family genes organized in a cluster on chromosome 1 The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens

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